Cure4CF Foundation - Developing a cure for Cystic Fibrosis

Cure4CF Foundation Limited ABN 71 136 956 137

Our research team based at the Women’s and Children’s Hospital in Adelaide has developed a potential cure for CF. Their approach uses gene transfer into the affected airway, to replace the defective gene that causes Cystic Fibrosis.

Importantly, this method is targeted to the airway stem cells, so that every new airway cell normally produced over the lifetime of the lung already has the corrected CF gene within it.

The team has shown their gene transfer techniques can work successfully in laboratory mice, and the research team is now scaling up their work to larger animal models that more closely simulate the needs and physiology of human lungs.

Associate Professor Donald S Anson, Phd

Head, Gene Technology Unit

Department of Genetic Medicine

Dr David Parsons, Phd

Principal Medical Scientist

Department of Pulmonary Medicine

Dr Greg Smith, MB.BS

Senior Staff Specialist, Clinical Director of CF Research

Department of Pulmonary Medicine

“Gene therapy is a new way of doing medicine and we are making exciting progress in this innovative research aimed at correcting the basic defect which causes CF lung disease. It may become a cure for CF.”

- Dr. D. Parsons, Chief Medical Scientist, Respiratory Medicine, WCH